Participants: Participants included 566 young adult women with Turner syndrome, aged 22.6 ± 2.6 yr (range, 18.3–31.2).
Main Outcome Measures: Measures used in the study were Coopersmith’s Self-Esteem Inventory, Social Adjustment Scale Self-Report, questions on sexual experience, and extensive data on pediatric management.
Late age at first kiss or date was associated with cardiac involvement and a lack of spontaneous pubertal development.
KLEIN, MD, MPH, San Antonio Military Medical Center, San Antonio, Texas MERRILY A.
However, some women have been able to become pregnant spontaneous and others with the aid of fertility programs.
Turner’s Syndrome or gonadal dysgenesis is a condition that affects females in which one of the sex chromosomes (X chromosome) is completely missing or has abnormalities.
A normal female has 46 chromosomes, including 2 X-chromosomes (44XX).
Most cases of secondary amenorrhea can be attributed to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, or primary ovarian insufficiency. Initial workup of primary and secondary amenorrhea includes a pregnancy test and serum levels of luteinizing hormone, follicle-stimulating hormone, prolactin, and thyroid-stimulating hormone.
Results: Low self-esteem was associated with otological involvement and limited sexual experience.
Low social adjustment was associated with lower paternal socioeconomic class and an absence of sexual experience.
Patients with polycystic ovary syndrome are at risk for glucose intolerance, dyslipidemia, and other aspects of metabolic syndrome.
Patients with Turner syndrome (or variant) should be treated by a physician familiar with the appropriate screening and treatment measures.